Stx11 | syntaxin 11

GeneMGI:1921982Synonyms: 5830405C08Rik

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Cardiovascular system Mortality/aging Renal/urinary system

13 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology1 supporting datasetStx11em1(IMPC)MbphomozygoteEarly adultN/A * 
increased heart weight2 supporting datasetsStx11em1(IMPC)MbphomozygoteEarly adult1.18x10-5 
increased blood urea nitrogen level1 supporting datasetStx11em1(IMPC)MbphomozygoteEarly adult5.57x10-8 
small kidney1 supporting datasetStx11em1(IMPC)MbphomozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance1 supporting datasetStx11em1(IMPC)MbphomozygoteEarly adultN/A * 
increased lymphocyte cell number1 supporting datasetStx11em1(IMPC)MbphomozygoteEarly adult5.28x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Stx11em1(IMPC)MbpExon Deletionmouse
Stx11tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Stx11tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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