Zfp871 | zinc finger protein 871

GeneMGI:1921793Synonyms: 9030612M13Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Embryo Growth/size/body region Vision/eye Behavior/neurological Mortality/aging Cardiovascular system

15 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues

Phenotypes

abnormal embryo size1 supporting datasetZfp871tm1b(EUCOMM)WtsihomozygoteE18.5N/A * 
increased grip strength1 supporting datasetZfp871tm1b(EUCOMM)WtsiheterozygoteEarly adult2.51x10-5 
preweaning lethality, complete penetrance3 supporting datasetsZfp871tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal retina inner nuclear layer morphology2 supporting datasetsZfp871tm1b(EUCOMM)WtsiheterozygoteEarly adult1.88x10-7 
embryonic growth retardation1 supporting datasetZfp871tm1b(EUCOMM)WtsihomozygoteE18.5N/A * 
decreased total retina thickness2 supporting datasetsZfp871tm1b(EUCOMM)WtsiheterozygoteEarly adult3.2x10-7 
abnormal retina blood vessel morphology1 supporting datasetZfp871tm1b(EUCOMM)WtsiheterozygoteEarly adult3.96x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp871tm1(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Zfp871tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Zfp871tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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