Gzf1 | GDNF-inducible zinc finger protein 1

GeneMGI:1921783Synonyms: 8430437G08Rik, Zfp336

Physiological systems

17 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Adipose tissue Growth/size/body region Limbs/digits/tail Hearing/vestibular/ear Vision/eye Hematopoietic system Skeleton Mortality/aging Cardiovascular system

6 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



short tibia	1 supporting dataset	Gzf1^em1(IMPC)Tcp	homozygote	Early adult	0
abnormal eye morphology	1 supporting dataset	Gzf1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased mean corpuscular volume	1 supporting dataset	Gzf1^em1(IMPC)Tcp	heterozygote	Early adult	1.25x10^-7
preweaning lethality, incomplete penetrance	3 supporting datasets	Gzf1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Gzf1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal auditory brainstem response	3 supporting datasets	Gzf1^em1(IMPC)Tcp	homozygote	Early adult	2.77x10^-6
abnormal bone structure	1 supporting dataset	Gzf1^em1(IMPC)Tcp	homozygote	Early adult	7.77x10^-5
cataract	1 supporting dataset	Gzf1^em1(IMPC)Tcp	heterozygote	Early adult	8.44x10^-7
abnormal lens morphology	1 supporting dataset	Gzf1^em1(IMPC)Tcp	heterozygote	Early adult	7x10^-7
decreased circulating alkaline phosphatase level	1 supporting dataset	Gzf1^em1(IMPC)Tcp	homozygote	Early adult	2.98x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gzf1.

Associated images

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Histopathology

There is no histopathology data found for Gzf1.

IMPC related publications

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External links

No external links available for Gzf1.

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*Gzf1^em1(IMPC)Tcp*	Intra-exon deletion	‌	mouse
*Gzf1^{tm368934(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes