Lrrc17 | leucine rich repeat containing 17

GeneMGI:1921761Synonyms: 4833425M04Rik, 6130400C22Rik, +1 more

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged epididymis	1 supporting dataset	Lrrc17^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	2 supporting datasets	Lrrc17^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Lrrc17^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Lrrc17^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Lrrc17^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	2 supporting datasets	Lrrc17^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased freezing behavior	1 supporting dataset	Lrrc17^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.98x10^-8
abnormal spleen morphology	2 supporting datasets	Lrrc17^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal gallbladder morphology	1 supporting dataset	Lrrc17^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased locomotor activity	2 supporting datasets	Lrrc17^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.41x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lrrc17.

Associated images

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Histopathology

There is no histopathology data found for Lrrc17.

IMPC related publications

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External links

No external links available for Lrrc17.

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*Lrrc17^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Lrrc17^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Lrrc17^{tm1.1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	ES Cell
*Lrrc17^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Lrrc17^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Lrrc17^{tm2(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Lrrc17^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Lrrc17^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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