Cfap53 | cilia and flagella associated protein 53

GeneMGI:1921703Synonyms: 4933415I03Rik, Ccdc11

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetCfap53em1(IMPC)WtsihomozygoteEarly adultN/A * 
increased grip strength1 supporting datasetCfap53em1(IMPC)WtsiheterozygoteEarly adult7.13x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Cfap53em1(IMPC)WtsiDeletionmouse
Cfap53tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cfap53tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cfap53tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cfap53tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Cfap53tm1e(KOMP)MbpTargeted, non-conditional allelees cell

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