Gle1 | GLE1 RNA export mediator

GeneMGI:1921662Synonyms: 4933405K21Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Cardiovascular system Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

5Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Gle1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased heart weight	1 supporting dataset	Gle1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	5.1x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gle1.

Associated images

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Histopathology

There is no histopathology data found for Gle1.

IMPC related publications

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External links

No external links available for Gle1.

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*Gle1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Gle1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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