Fhip1b | FHF complex subunit HOOK interacting protein 1B

GeneMGI:1921599Synonyms: Fam160a2, 4632419K20Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

13 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Vision/eye Hematopoietic system Behavior/neurological Skeleton Craniofacial Cardiovascular system Renal/urinary system

7 No significant impact

4 Not tested

Gene metrics:17Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetFhip1bem1(IMPC)TcphomozygoteEarly adultN/A * 
decreased exploration in new environment2 supporting datasetsFhip1bem1(IMPC)TcphomozygoteEarly adult2.56x10-8 
abnormal stomach morphology1 supporting datasetFhip1bem1(IMPC)TcphomozygoteLate adultN/A * 
abnormal ovary morphology1 supporting datasetFhip1bem1(IMPC)TcphomozygoteLate adultN/A * 
decreased circulating alkaline phosphatase level1 supporting datasetFhip1bem1(IMPC)TcphomozygoteLate adult7.15x10-5 
abnormal sternum morphology1 supporting datasetFhip1bem1(IMPC)TcphomozygoteLate adultN/A * 
enlarged urinary bladder1 supporting datasetFhip1bem1(IMPC)TcphomozygoteLate adultN/A * 
decreased locomotor activity3 supporting datasetsFhip1bem1(IMPC)TcphomozygoteEarly adult9.18x10-6 
abnormal tooth morphology1 supporting datasetFhip1bem1(IMPC)TcphomozygoteEarly adult2.56x10-6 
decreased exploration in new environment1 supporting datasetFhip1bem1(IMPC)TcphomozygoteMiddle aged adult9.5x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fhip1bem1(IMPC)TcpInter-exon deletionmouse

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