Dnajc14 | DnaJ heat shock protein family (Hsp40) member C14

GeneMGI:1921580Synonyms: HDJ3, LIP6, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hearing/vestibular/ear Behavior/neurological

13 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

abnormal auditory brainstem response1 supporting datasetDnajc14tm1.1(KOMP)VlcghomozygoteEarly adult1.16x10-6 
increased lean body mass1 supporting datasetDnajc14tm1.1(KOMP)VlcghomozygoteEarly adult6.13x10-5 
abnormal sleep behavior1 supporting datasetDnajc14tm1.1(KOMP)VlcghomozygoteEarly adult4.72x10-5 
increased circulating chloride level1 supporting datasetDnajc14tm1.1(KOMP)VlcghomozygoteEarly adult8.59x10-5 
increased circulating sodium level1 supporting datasetDnajc14tm1.1(KOMP)VlcghomozygoteEarly adult3.56x10-5 
decreased circulating serum albumin level1 supporting datasetDnajc14tm1.1(KOMP)VlcghomozygoteEarly adult2.62x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dnajc14tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Dnajc14tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Dnajc14tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dnajc14tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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