Gpn1 | GPN-loop GTPase 1
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Mortality/aging
14 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Gpn1em1(IMPC)J | homozygote | Early adult | N/A * | ||
| decreased circulating aspartate transaminase level | 1 supporting dataset | Gpn1em1(IMPC)J | heterozygote | Early adult | 2.73x10-5 | ||
| decreased mean corpuscular volume | 1 supporting dataset | Gpn1em1(IMPC)J | heterozygote | Early adult | 2.96x10-6 | ||
| decreased circulating bilirubin level | 1 supporting dataset | Gpn1em1(IMPC)J | heterozygote | Early adult | 3.2x10-5 | ||
| increased circulating glucose level | 1 supporting dataset | Gpn1em1(IMPC)J | heterozygote | Early adult | 4.09x10-5 |
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External links
No external links available for Gpn1.
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| Gpn1em1(IMPC)J | Exon Deletion | | mouse |
| Gpn1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Gpn1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Gpn1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Gpn1tm46199(L1L2_gt1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |