Tubgcp2 | tubulin, gamma complex component 2

GeneMGI:1921487Synonyms: 1700022B05Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Skeleton Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal bone structure1 supporting datasetTubgcp2em1(IMPC)BayheterozygoteEarly adult1.29x10-5 
preweaning lethality, complete penetrance3 supporting datasetsTubgcp2em1(IMPC)TcphomozygoteEarly adultN/A * 
preweaning lethality, complete penetrance3 supporting datasetsTubgcp2em1(IMPC)BayhomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetTubgcp2em1(IMPC)TcphomozygoteE9.5N/A * 
abnormal sternum morphology1 supporting datasetTubgcp2em1(IMPC)TcpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tubgcp2em1(IMPC)BayExon Deletionmouse
Tubgcp2em1(IMPC)TcpExon Deletionmouse
Tubgcp2tm119211(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Tubgcp2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tubgcp2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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