Cmtr1 | cap methyltransferase 1

GeneMGI:1921407Synonyms: 1300018I05Rik, Ftsjd2

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Growth/size/body region Mortality/aging Cardiovascular system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetCmtr1em1(IMPC)JhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetCmtr1em1(IMPC)JhomozygoteEarly adultN/A * 
increased heart weight1 supporting datasetCmtr1em1(IMPC)JheterozygoteEarly adult5.02x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cmtr1em1(IMPC)JExon Deletionmouse
Cmtr1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cmtr1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Cmtr1tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cmtr1tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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