Acot12 | acyl-CoA thioesterase 12

GeneMGI:1921406Synonyms: 4930449F15Rik, 1300004O04Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Muscle Behavior/neurological Cardiovascular system

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased cardiac muscle contractility	1 supporting dataset	Acot12^{em1(IMPC)Hmgu}	homozygote	Early adult	5.8x10^-5
abnormal vocalization	1 supporting dataset	Acot12^{em1(IMPC)Hmgu}	homozygote	Early adult	1.02x10^-6
dilated heart left ventricle	1 supporting dataset	Acot12^{em1(IMPC)Hmgu}	homozygote	Early adult	4.33x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Acot12.

Associated images

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Histopathology

There is no histopathology data found for Acot12.

IMPC related publications

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External links

No external links available for Acot12.

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*Acot12^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Acot12^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Acot12^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Acot12^{tm43067(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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