Acoxl | acyl-Coenzyme A oxidase-like

GeneMGI:1921371Synonyms: 1200014P05Rik

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Cardiovascular system

11 No significant impact

4 Not tested

Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal spleen morphology1 supporting datasetAcoxlem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal lymph node morphology1 supporting datasetAcoxlem1(IMPC)MbphomozygoteLate adultN/A * 
small heart1 supporting datasetAcoxlem1(IMPC)MbphomozygoteLate adultN/A * 
improved glucose tolerance1 supporting datasetAcoxlem1(IMPC)MbphomozygoteLate adult2.55x10-5 
decreased lymphocyte cell number1 supporting datasetAcoxlem1(IMPC)MbphomozygoteEarly adult5.31x10-7 
enlarged lymph nodes1 supporting datasetAcoxlem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal adrenal gland morphology1 supporting datasetAcoxlem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetAcoxlem1(IMPC)MbphomozygoteLate adultN/A * 
enlarged spleen2 supporting datasetsAcoxlem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal liver morphology1 supporting datasetAcoxlem1(IMPC)MbphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Acoxlem1(IMPC)MbpExon Deletionmouse
Acoxltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Acoxltm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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