Acoxl | acyl-Coenzyme A oxidase-like
Physiological systems
20 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Cardiovascular system
11 No significant impact
4 Not tested
Data collections
Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal spleen morphology | 1 supporting dataset | Acoxlem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| abnormal lymph node morphology | 1 supporting dataset | Acoxlem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| small heart | 1 supporting dataset | Acoxlem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| improved glucose tolerance | 1 supporting dataset | Acoxlem1(IMPC)Mbp | homozygote | Late adult | 2.55x10-5 | ||
| decreased lymphocyte cell number | 1 supporting dataset | Acoxlem1(IMPC)Mbp | homozygote | Early adult | 5.31x10-7 | ||
| enlarged lymph nodes | 1 supporting dataset | Acoxlem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| abnormal adrenal gland morphology | 1 supporting dataset | Acoxlem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Acoxlem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| enlarged spleen | 2 supporting datasets | Acoxlem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| abnormal liver morphology | 1 supporting dataset | Acoxlem1(IMPC)Mbp | homozygote | Late adult | N/A * |
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Human diseases caused by Acoxl mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Acoxl.
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| Acoxlem1(IMPC)Mbp | Exon Deletion | | mouse |
| Acoxltm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Acoxltm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |