Usp16 | ubiquitin specific peptidase 16

GeneMGI:1921362Synonyms: 1200004E02Rik, 6330514E22Rik, +2 more

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Hematopoietic system

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased eosinophil cell number2 supporting datasetsUsp16tm1b(EUCOMM)HmguheterozygoteEarly adult1.14x10-7 
increased basophil cell number2 supporting datasetsUsp16tm1b(EUCOMM)HmguheterozygoteEarly adult4.98x10-8 
decreased mean platelet volume1 supporting datasetUsp16tm1b(EUCOMM)HmguheterozygoteEarly adult4.43x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Usp16tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Usp16tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Usp16tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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