Plce1 | phospholipase C, epsilon 1

GeneMGI:1921305Synonyms: 4933403A21Rik, PLCepsilon

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Hematopoietic system Cardiovascular system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal skin morphology	1 supporting dataset	Plce1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased heart weight	2 supporting datasets	Plce1^em1(IMPC)Mbp	homozygote	Early adult	7.94x10^-11
prolonged QRS complex duration	1 supporting dataset	Plce1^em1(IMPC)Mbp	homozygote	Early adult	9.76x10^-5
increased neutrophil cell number	2 supporting datasets	Plce1^em1(IMPC)Mbp	homozygote	Early adult	2.83x10^-9
decreased lymphocyte cell number	1 supporting dataset	Plce1^em1(IMPC)Mbp	homozygote	Early adult	3.89x10^-5
increased monocyte cell number	1 supporting dataset	Plce1^em1(IMPC)Mbp	homozygote	Early adult	7.35x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Plce1.

Associated images

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Histopathology

There is no histopathology data found for Plce1.

IMPC related publications

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External links

No external links available for Plce1.

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*Plce1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Plce1^{tm458995(L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes