Plce1 | phospholipase C, epsilon 1
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Integument Growth/size/body region Hematopoietic system Cardiovascular system
15 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal skin morphology | 1 supporting dataset | Plce1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| increased heart weight | 2 supporting datasets | Plce1em1(IMPC)Mbp | homozygote | Early adult | 7.94x10-11 | ||
| prolonged QRS complex duration | 1 supporting dataset | Plce1em1(IMPC)Mbp | homozygote | Early adult | 9.76x10-5 | ||
| increased neutrophil cell number | 2 supporting datasets | Plce1em1(IMPC)Mbp | homozygote | Early adult | 2.83x10-9 | ||
| decreased lymphocyte cell number | 1 supporting dataset | Plce1em1(IMPC)Mbp | homozygote | Early adult | 3.89x10-5 | ||
| increased monocyte cell number | 1 supporting dataset | Plce1em1(IMPC)Mbp | homozygote | Early adult | 7.35x10-7 |
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This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Plce1.
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| Plce1em1(IMPC)Mbp | Exon Deletion | | mouse |
| Plce1tm458995(L1L2_GT0_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |