Rd3 | retinal degeneration 3

GeneMGI:1921273Synonyms: rd3, rd-3, +1 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Hematopoietic system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetRd3em1(IMPC)BayhomozygoteEarly adult3.07x10-12 
increased hematocrit1 supporting datasetRd3em1(IMPC)BayhomozygoteEarly adult1.27x10-6 
abnormal eye anterior chamber depth1 supporting datasetRd3em1(IMPC)BayhomozygoteEarly adult1.63x10-10 
abnormal retina inner nuclear layer morphology2 supporting datasetsRd3em1(IMPC)BayhomozygoteEarly adult9.48x10-5 
decreased mean corpuscular hemoglobin concentration1 supporting datasetRd3em1(IMPC)BayhomozygoteEarly adult3.4x10-5 
abnormal retina outer nuclear layer morphology2 supporting datasetsRd3em1(IMPC)BayhomozygoteEarly adult3.25x10-153 
decreased total retina thickness2 supporting datasetsRd3em1(IMPC)BayhomozygoteEarly adult2.54x10-119 
abnormal eye posterior chamber depth1 supporting datasetRd3em1(IMPC)BayhomozygoteEarly adult2.5x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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