Glyr1 | glyoxylate reductase 1 homolog (Arabidopsis)

GeneMGI:1921272Synonyms: 3930401K13Rik, 2810419J22Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Immune system Integument Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Behavior/neurological Skeleton Renal/urinary system

11 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin concentration1 supporting datasetGlyr1em1(IMPC)TcpheterozygoteEarly adult4.35x10-5 
impaired pupillary reflex1 supporting datasetGlyr1em1(IMPC)TcphomozygoteEarly adult4.02x10-5 
abnormal iris morphology1 supporting datasetGlyr1em1(IMPC)TcphomozygoteEarly adult2.59x10-6 
abnormal skin morphology2 supporting datasetsGlyr1em1(IMPC)TcphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetGlyr1em1(IMPC)TcphomozygoteEarly adultN/A * 
short tibia1 supporting datasetGlyr1em1(IMPC)TcphomozygoteEarly adult1.1x10-6 
polycystic kidney1 supporting datasetGlyr1em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Glyr1em1(IMPC)TcpExon Deletionmouse
Glyr1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Glyr1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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