Traf3ip1 | TRAF3 interacting protein 1
Physiological systems
14 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Vision/eye Mortality/aging Cardiovascular system
8 No significant impact
10 Not tested
Data collections
Gene metrics:10Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Traf3ip1em1(IMPC)Bay | homozygote | E12.5 | N/A * | ||
| edema | 1 supporting dataset | Traf3ip1em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Traf3ip1em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Traf3ip1em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal embryo turning | 1 supporting dataset | Traf3ip1em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Traf3ip1em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal pericardium morphology | 1 supporting dataset | Traf3ip1em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Traf3ip1em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal somite shape | 1 supporting dataset | Traf3ip1em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| increased cornea thickness | 1 supporting dataset | Traf3ip1em1(IMPC)Bay | heterozygote | Early adult | 2.63x10-5 |
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External links
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| Traf3ip1em1(IMPC)Bay | Exon Deletion | | mouse |
| Traf3ip1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Traf3ip1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |