Psmb11 | proteasome (prosome, macropain) subunit, beta type, 11

GeneMGI:1921152Synonyms: 5830406J20Rik, beta5t

Physiological systems

23 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Digestive/alimentary Limbs/digits/tail Hematopoietic system Cardiovascular system

14 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:21Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal thymus morphology	1 supporting dataset	Psmb11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal ileum morphology	1 supporting dataset	Psmb11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Psmb11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased NK T cell number	1 supporting dataset	Psmb11^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.05x10^-6
small testis	1 supporting dataset	Psmb11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased CD8-positive, alpha-beta T cell number	1 supporting dataset	Psmb11^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.32x10^-21
enlarged heart	1 supporting dataset	Psmb11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	2 supporting datasets	Psmb11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased effector memory T-helper cell number	1 supporting dataset	Psmb11^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.83x10^-5
increased T-helper cell number	1 supporting dataset	Psmb11^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.48x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Psmb11.

Associated images

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Histopathology

There is no histopathology data found for Psmb11.

IMPC related publications

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External links

No external links available for Psmb11.

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*Psmb11^{em1(IMPC)Ccpcz}*	Inter-exon deletion	‌	mouse

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