Eif3k | eukaryotic translation initiation factor 3, subunit K

GeneMGI:1921080Synonyms: Eif3s12, eIF3K, +1 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Skeleton Craniofacial Mortality/aging Cardiovascular system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating total protein level	1 supporting dataset	Eif3k^{em1(IMPC)Hmgu}	heterozygote	Early adult	5.48x10^-5
abnormal tooth morphology	2 supporting datasets	Eif3k^{em1(IMPC)Hmgu}	heterozygote	Early adult	1.46x10^-9
prolonged RR interval	1 supporting dataset	Eif3k^{em1(IMPC)Hmgu}	heterozygote	Early adult	2.48x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Eif3k^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Eif3k.

Associated images

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Histopathology

There is no histopathology data found for Eif3k.

IMPC related publications

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External links

No external links available for Eif3k.

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*Eif3k^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Eif3k^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Eif3k^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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