Rbm20 | RNA binding motif protein 20

GeneMGI:1920963Synonyms: 1110018J23Rik, 2010003H22Rik

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Nervous system Vision/eye Hematopoietic system Cardiovascular system

14 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating triglyceride level1 supporting datasetRbm20em1(IMPC)MbphomozygoteEarly adult2.25x10-5 
absent optic nerve1 supporting datasetRbm20em1(IMPC)MbphomozygoteEarly adultN/A * 
small spleen1 supporting datasetRbm20em1(IMPC)MbphomozygoteEarly adultN/A * 
cataract1 supporting datasetRbm20em1(IMPC)MbphomozygoteEarly adult1.36x10-5 
abnormal retina morphology1 supporting datasetRbm20em1(IMPC)MbphomozygoteEarly adult2.94x10-5 
abnormal vitreous body morphology1 supporting datasetRbm20em1(IMPC)MbphomozygoteEarly adult1.63x10-5 
abnormal heart shape1 supporting datasetRbm20em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rbm20em1(IMPC)MbpExon Deletionmouse
Rbm20tm82933(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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