Ppp2r1b | protein phosphatase 2, regulatory subunit A, beta
Physiological systems
16 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Growth/size/body region Hematopoietic system Skeleton Craniofacial
9 No significant impact
8 Not tested
Data collections
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased basophil cell number | 2 supporting datasets | Ppp2r1btm1b(EUCOMM)Wtsi | homozygote | Early adult | 6.36x10-20 | ||
| abnormal tooth morphology | 1 supporting dataset | Ppp2r1btm1b(EUCOMM)Wtsi | homozygote | Early adult | 9.85x10-5 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Ppp2r1btm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.28x10-5 | ||
| increased eosinophil cell number | 2 supporting datasets | Ppp2r1btm1b(EUCOMM)Wtsi | homozygote | Early adult | 6.06x10-11 | ||
| male infertility | 1 supporting dataset | Ppp2r1btm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Ppp2r1b.
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| Ppp2r1btm1(NCOM)Cmhd | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Ppp2r1btm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ppp2r1btm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |