Psma8 | proteasome subunit alpha 8

GeneMGI:1920927Synonyms: 2410072D24Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Renal/urinary system

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small testis	1 supporting dataset	Psma8^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Psma8^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
small epididymis	1 supporting dataset	Psma8^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
male infertility	1 supporting dataset	Psma8^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased monocyte cell number	1 supporting dataset	Psma8^em1(IMPC)Tcp	homozygote	Early adult	3.08x10^-5
small thymus	1 supporting dataset	Psma8^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Psma8^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Psma8^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal pancreas morphology	1 supporting dataset	Psma8^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Psma8^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Psma8.

Associated images

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Histopathology

There is no histopathology data found for Psma8.

IMPC related publications

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External links

No external links available for Psma8.

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*Psma8^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Psma8^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Psma8^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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