Mipol1 | mirror-image polydactyly 1

GeneMGI:1920740Synonyms: 1700081O04Rik, 6030439O22Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Vision/eye Behavior/neurological Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	1 supporting dataset	Mipol1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.64x10^-5
abnormal retina vasculature morphology	1 supporting dataset	Mipol1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.8x10^-5
decreased prepulse inhibition	3 supporting datasets	Mipol1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.82x10^-7
increased circulating lipase level	1 supporting dataset	Mipol1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.39x10^-5
abnormal lens morphology	2 supporting datasets	Mipol1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.26x10^-6
increased circulating aspartate transaminase level	1 supporting dataset	Mipol1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.77x10^-9
cataract	1 supporting dataset	Mipol1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mipol1.

Associated images

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Histopathology

There is no histopathology data found for Mipol1.

IMPC related publications

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External links

No external links available for Mipol1.

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*Mipol1^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Mipol1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Mipol1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mipol1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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