Ptchd4 | patched domain containing 4

GeneMGI:1920485Synonyms: 3110082D06Rik

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Integument Growth/size/body region Limbs/digits/tail Respiratory system Cardiovascular system

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged heart1 supporting datasetPtchd4em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetPtchd4em1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased lung elastance1 supporting datasetPtchd4em1(IMPC)CcpczhomozygoteEarly adult7.31x10-5 
abnormal digit morphology1 supporting datasetPtchd4em1(IMPC)CcpczhomozygoteEarly adult4.99x10-8 
abnormal heart morphology1 supporting datasetPtchd4em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ptchd4em1(IMPC)CcpczExon Deletionmouse
Ptchd4tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Ptchd4tm2e(EUCOMM)HmguTargeted, non-conditional allelees cell

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