Xpot | exportin, tRNA (nuclear export receptor for tRNAs)

GeneMGI:1920442Synonyms: EXPORTIN-T, C79645, +1 more

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Embryo Growth/size/body region Behavior/neurological Mortality/aging Craniofacial

16 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues

Phenotypes

abnormal embryo size1 supporting datasetXpottm3b(EUCOMM)HmguhomozygoteE18.5N/A * 
unresponsive to tactile stimuli1 supporting datasetXpottm3b(EUCOMM)HmguhomozygoteE18.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetXpottm3b(EUCOMM)HmguhomozygoteEarly adultN/A * 
unresponsive to tactile stimuli1 supporting datasetXpottm3b(EUCOMM)HmguheterozygoteE18.5N/A * 
abnormal facial morphology2 supporting datasetsXpottm3b(EUCOMM)HmguhomozygoteE18.5N/A * 
preweaning lethality, incomplete penetrance2 supporting datasetsXpottm3b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Xpottm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Xpottm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Xpottm3a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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Xpottm3b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Xpottm3e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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