Tm7sf2 | transmembrane 7 superfamily member 2

GeneMGI:1920416Synonyms: ANG1, 3110041O18Rik

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hematopoietic system Behavior/neurological

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased eosinophil cell number1 supporting datasetTm7sf2tm1b(KOMP)WtsihomozygoteEarly adult2.59x10-6 
decreased lymphocyte cell number1 supporting datasetTm7sf2tm1b(KOMP)WtsihomozygoteEarly adult7.02x10-7 
increased vertical activity1 supporting datasetTm7sf2tm1b(KOMP)WtsihomozygoteEarly adult2.15x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tm7sf2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Tm7sf2tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Tm7sf2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Tm7sf2tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tm7sf2tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Tm7sf2tm95256(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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