Prss57 | serine protease 57

GeneMGI:1920356Synonyms: GLGL782, UNQ782, +2 more

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Nervous system Respiratory system Hematopoietic system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased prepulse inhibition	1 supporting dataset	Prss57^{em1(IMPC)Ccpcz}	homozygote	Early adult	7x10^-6
hydrometra	1 supporting dataset	Prss57^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased NK T cell number	1 supporting dataset	Prss57^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.2x10^-5
abnormal uterus morphology	1 supporting dataset	Prss57^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased lung tissue damping	1 supporting dataset	Prss57^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.71x10^-5
abnormal thymus morphology	1 supporting dataset	Prss57^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Prss57^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prss57.

Associated images

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Histopathology

There is no histopathology data found for Prss57.

IMPC related publications

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External links

No external links available for Prss57.

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*Prss57^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Prss57^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Prss57^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Prss57^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Prss57^{tm83701(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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