Emc7 | ER membrane protein complex subunit 7

GeneMGI:1920274Synonyms: 2900064A13Rik

Physiological systems

1 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

23 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:1Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetEmc7tm1b(KOMP)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

Human diseases caused by Emc7 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Emc7tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Emc7tm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Emc7tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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