Rnf169 | ring finger protein 169

GeneMGI:1920257Synonyms: 2900057K09Rik

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased bone mineral content	1 supporting dataset	Rnf169^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	3.9x10^-7
abnormal bone mineralization	1 supporting dataset	Rnf169^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.71x10^-9
increased startle reflex	1 supporting dataset	Rnf169^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	3.66x10^-7
increased lean body mass	1 supporting dataset	Rnf169^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.66x10^-5
decreased CD8-positive, alpha-beta T cell number	1 supporting dataset	Rnf169^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	5.08x10^-5
increased monocyte cell number	1 supporting dataset	Rnf169^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	7.54x10^-8
decreased bone mineral density	1 supporting dataset	Rnf169^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	8.5x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnf169.

Associated images

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Histopathology

There is no histopathology data found for Rnf169.

IMPC related publications

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External links

No external links available for Rnf169.

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*Rnf169^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Rnf169^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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