Ift25 | intraflagellar transport 25

GeneMGI:1920188Synonyms: Hspb11, 2900042B11Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	2 supporting datasets	Ift25^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating glycerol level	1 supporting dataset	Ift25^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	3.23x10^-5
increased circulating free fatty acids level	1 supporting dataset	Ift25^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	9.08x10^-7
increased circulating LDL cholesterol level	1 supporting dataset	Ift25^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.21x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ift25.

Associated images

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Histopathology

There is no histopathology data found for Ift25.

IMPC related publications

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External links

No external links available for Ift25.

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*Ift25^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ift25^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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