Macrod2 | mono-ADP ribosylhydrolase 2

GeneMGI:1920149Synonyms: 1110033L15Rik, 2900006F19Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
0Embryo tissues

Phenotypes

decreased thigmotaxis2 supporting datasetsMacrod2tm1.1(KOMP)VlcghomozygoteEarly adult7.69x10-5 
hyperactivity8 supporting datasetsMacrod2tm1.1(KOMP)VlcghomozygoteEarly adult2.99x10-13 
increased fasting circulating glucose level1 supporting datasetMacrod2tm1.1(KOMP)VlcghomozygoteEarly adult1.82x10-8 
decreased circulating glucose level1 supporting datasetMacrod2tm1.1(KOMP)VlcgheterozygoteEarly adult9.52x10-6 
increased vertical activity1 supporting datasetMacrod2tm1.1(KOMP)VlcghomozygoteEarly adult3.92x10-20 
hyperactivity2 supporting datasetsMacrod2tm1.1(KOMP)VlcgheterozygoteEarly adult3.93x10-5 
abnormal retina morphology1 supporting datasetMacrod2tm1.1(KOMP)VlcghomozygoteEarly adult6.93x10-5 
increased fasting circulating glucose level1 supporting datasetMacrod2tm1.1(KOMP)VlcgheterozygoteEarly adult7.08x10-8 
increased hemoglobin content1 supporting datasetMacrod2tm1.1(KOMP)VlcghomozygoteEarly adult5.4x10-5 
increased blood urea nitrogen level1 supporting datasetMacrod2tm1.1(KOMP)VlcghomozygoteEarly adult5.81x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  
Rows per page: 










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Macrod2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Macrod2tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter