Setd5 | SET domain containing 5

GeneMGI:1920145Synonyms: 2900045N06Rik

Physiological systems

18 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Immune system Integument Growth/size/body region Hearing/vestibular/ear Hematopoietic system Behavior/neurological Skeleton Mortality/aging Craniofacial

7 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal tooth morphology	1 supporting dataset	Setd5^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	3.9x10^-6
abnormal coat/hair pigmentation	2 supporting datasets	Setd5^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.66x10^-9
decreased grip strength	1 supporting dataset	Setd5^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	7.49x10^-5
abnormal snout morphology	2 supporting datasets	Setd5^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	8.23x10^-11
abnormal auditory brainstem response	3 supporting datasets	Setd5^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.13x10^-7
increased regulatory T cell number	1 supporting dataset	Setd5^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*
increased monocyte cell number	1 supporting dataset	Setd5^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*
absent pinna reflex	1 supporting dataset	Setd5^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	9.77x10^-6
abnormal incisor morphology	1 supporting dataset	Setd5^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.43x10^-6
decreased circulating glucose level	1 supporting dataset	Setd5^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	7x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Setd5.

Associated images

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Histopathology

There is no histopathology data found for Setd5.

IMPC related publications

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External links

No external links available for Setd5.

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*Setd5^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Setd5^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Setd5^{tm39685(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Setd5^{tm39685(L1L2_st2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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