Ttc39c | tetratricopeptide repeat domain 39C
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Vision/eye Hematopoietic system Skeleton
14 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased hematocrit | 1 supporting dataset | Ttc39cem1(IMPC)J | homozygote | Early adult | 2.24x10-5 | ||
| increased erythrocyte cell number | 1 supporting dataset | Ttc39cem1(IMPC)J | homozygote | Early adult | 5.76x10-5 | ||
| decreased bone mineral density | 1 supporting dataset | Ttc39cem1(IMPC)J | homozygote | Early adult | 4.31x10-5 | ||
| irregularly shaped pupil | 1 supporting dataset | Ttc39cem1(IMPC)J | homozygote | Early adult | 2.75x10-5 |
| | | | | | | | | | |
Human diseases caused by Ttc39c mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Ttc39c.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Ttc39cem1(IMPC)J | Exon Deletion | | mouse |
| Ttc39ctm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ttc39ctm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Ttc39ctm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ttc39ctm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |