Skida1 | SKI/DACH domain containing 1

GeneMGI:1919918Synonyms: 2810030E01Rik, 5730507N06Rik

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Hematopoietic system Skeleton Mortality/aging

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:43Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



decreased erythrocyte cell number	1 supporting dataset	Skida1^{tm1(KOMP)Wtsi}	heterozygote	Early adult	8.41x10^-16
enlarged lymph nodes	2 supporting datasets	Skida1^{tm1.1(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Skida1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Skida1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Skida1^{tm1.1(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
decreased hemoglobin content	1 supporting dataset	Skida1^{tm1(KOMP)Wtsi}	heterozygote	Early adult	6.84x10^-14
abnormal vertebral arch morphology	1 supporting dataset	Skida1^{tm1(KOMP)Wtsi}	heterozygote	Early adult	1.62x10^-5
increased mean corpuscular hemoglobin	1 supporting dataset	Skida1^{tm1(KOMP)Wtsi}	heterozygote	Early adult	8.92x10^-5
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Skida1^{tm1(KOMP)Wtsi}	heterozygote	Early adult	5.09x10^-8
decreased hematocrit	1 supporting dataset	Skida1^{tm1(KOMP)Wtsi}	heterozygote	Early adult	1.08x10^-17

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Skida1.

Associated images

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Histopathology

There is no histopathology data found for Skida1.

IMPC related publications

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External links

No external links available for Skida1.

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*Skida1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Skida1^{tm1.1(KOMP)Wtsi}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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