Ppme1 | protein phosphatase methylesterase 1

GeneMGI:1919840Synonyms: 1110069N17Rik, PME-1, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Liver/biliary system Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal liver morphology	1 supporting dataset	Ppme1^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Ppme1^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*
increased circulating triglyceride level	1 supporting dataset	Ppme1^{em1(IMPC)Rbrc}	heterozygote	Early adult	1.17x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ppme1.

Associated images

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Histopathology

There is no histopathology data found for Ppme1.

IMPC related publications

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External links

No external links available for Ppme1.

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*Ppme1^{em1(IMPC)Rbrc}*	Exon Deletion	‌	mouse
*Ppme1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ppme1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ppme1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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