Rcc2 | regulator of chromosome condensation 2

GeneMGI:1919784Synonyms: 2610510H01Rik, 2610529N02Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument Growth/size/body region Nervous system Vision/eye Hematopoietic system Cardiovascular system

11 No significant impact

5 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

decreased circulating serum albumin level1 supporting datasetRcc2tm1b(EUCOMM)WtsihomozygoteEarly adult1.78x10-5 
abnormal coat/hair pigmentation1 supporting datasetRcc2tm1b(EUCOMM)WtsihomozygoteEarly adult6.67x10-8 
decreased mean corpuscular volume1 supporting datasetRcc2tm1b(EUCOMM)WtsihomozygoteEarly adult8.76x10-7 
increased heart weight1 supporting datasetRcc2tm1b(EUCOMM)WtsihomozygoteEarly adult1.41x10-5 
abnormal optic disk morphology1 supporting datasetRcc2tm1b(EUCOMM)WtsihomozygoteEarly adult2.4x10-5 
abnormal retina morphology1 supporting datasetRcc2tm1b(EUCOMM)WtsihomozygoteEarly adult6.04x10-5 
decreased circulating total protein level1 supporting datasetRcc2tm1b(EUCOMM)WtsihomozygoteEarly adult4.18x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rcc2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Rcc2tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Rcc2tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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