Atxn7l2 | ataxin 7-like 2
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Behavior/neurological Skeleton
16 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal eye morphology | 1 supporting dataset | Atxn7l2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| increased grip strength | 1 supporting dataset | Atxn7l2em1(IMPC)Mbp | homozygote | Early adult | 1.63x10-5 | ||
| increased circulating HDL cholesterol level | 1 supporting dataset | Atxn7l2em1(IMPC)Mbp | homozygote | Early adult | 7.52x10-7 | ||
| increased circulating calcium level | 1 supporting dataset | Atxn7l2em1(IMPC)Mbp | homozygote | Early adult | 9.74x10-5 | ||
| increased freezing behavior | 1 supporting dataset | Atxn7l2em1(IMPC)Mbp | homozygote | Early adult | 2.11x10-8 | ||
| increased bone mineral content | 1 supporting dataset | Atxn7l2em1(IMPC)Mbp | homozygote | Early adult | 1.15x10-7 |
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Human diseases caused by Atxn7l2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Atxn7l2.
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| Atxn7l2em1(IMPC)Mbp | Inter-exon deletion | | mouse |