Lypd3 | Ly6/Plaur domain containing 3

GeneMGI:1919684Synonyms: 2310061G07Rik, C4.4A

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating triglyceride level	1 supporting dataset	Lypd3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	7.95x10^-10
increased food intake	1 supporting dataset	Lypd3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.49x10^-7
preweaning lethality, incomplete penetrance	3 supporting datasets	Lypd3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased blood urea nitrogen level	1 supporting dataset	Lypd3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.15x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lypd3.

Associated images

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Histopathology

There is no histopathology data found for Lypd3.

IMPC related publications

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External links

No external links available for Lypd3.

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*Lypd3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Lypd3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Lypd3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Lypd3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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