B4gat1 | beta-1,4-glucuronyltransferase 1

GeneMGI:1919680Synonyms: 1500032M01Rik, B3gnt1, +3 more

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

20 No significant impact

2 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
30Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetB4gat1tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsB4gat1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetB4gat1tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
hyperactivity1 supporting datasetB4gat1tm1.1(KOMP)VlcgheterozygoteEarly adult6.3x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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B4gat1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
B4gat1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
B4gat1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
B4gat1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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