Aif1l | allograft inflammatory factor 1-like

GeneMGI:1919598Synonyms: 2810003C17Rik

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system

13 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
0Embryo tissues

Phenotypes

abnormal spleen morphology1 supporting datasetAif1ltm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetAif1ltm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal liver morphology1 supporting datasetAif1ltm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased spleen weight1 supporting datasetAif1ltm1b(EUCOMM)WtsihomozygoteEarly adult7.22x10-8 
abnormal retina outer nuclear layer morphology1 supporting datasetAif1ltm1b(EUCOMM)WtsihomozygoteEarly adult6.62x10-5 
enlarged spleen1 supporting datasetAif1ltm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
small thymus1 supporting datasetAif1ltm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Aif1ltm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Aif1ltm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Aif1ltm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Aif1ltm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Aif1ltm39300(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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