Aif1l | allograft inflammatory factor 1-like
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system
13 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
0Embryo tissues
| abnormal spleen morphology | 1 supporting dataset | Aif1ltm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Aif1ltm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal liver morphology | 1 supporting dataset | Aif1ltm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased spleen weight | 1 supporting dataset | Aif1ltm1b(EUCOMM)Wtsi | homozygote | Early adult | 7.22x10-8 | ||
| abnormal retina outer nuclear layer morphology | 1 supporting dataset | Aif1ltm1b(EUCOMM)Wtsi | homozygote | Early adult | 6.62x10-5 | ||
| enlarged spleen | 1 supporting dataset | Aif1ltm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| small thymus | 1 supporting dataset | Aif1ltm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | n/a | 0.19% (1/533) |
| bone | heterozygote | n/a | 0% (0/2) | 0% (0/394) |
| brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 0% (0/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
| cecum | heterozygote | n/a | 0% (0/2) | 7.75% (22/284) |
| cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 0% (0/2) | 0.41% (2/491) |
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Aif1l.
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| Aif1ltm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Aif1ltm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Aif1ltm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Aif1ltm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Aif1ltm39300(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |