Rusc1 | RUN and SH3 domain containing 1

GeneMGI:1919546Synonyms: 2210403N08Rik

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Adipose tissue Vision/eye Hematopoietic system Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral content1 supporting datasetRusc1em1(IMPC)JhomozygoteEarly adult3.18x10-5 
decreased total body fat amount1 supporting datasetRusc1em1(IMPC)JhomozygoteEarly adult1.13x10-5 
increased mean corpuscular hemoglobin concentration1 supporting datasetRusc1em1(IMPC)JhomozygoteEarly adult4.17x10-6 
persistence of hyaloid vascular system1 supporting datasetRusc1em1(IMPC)JhomozygoteEarly adult3.32x10-6 
decreased mean corpuscular volume1 supporting datasetRusc1em1(IMPC)JhomozygoteEarly adult2.19x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rusc1em1(IMPC)JExon Deletionmouse
Rusc1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Rusc1tm114953(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Rusc1tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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