Otud6b | OTU domain containing 6B

GeneMGI:1919451Synonyms: 2600013N14Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hematopoietic system Mortality/aging

17 No significant impact

4 Not tested

Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

increased basophil cell number2 supporting datasetsOtud6btm1b(EUCOMM)WtsiheterozygoteEarly adult1.71x10-19 
preweaning lethality, incomplete penetrance1 supporting datasetOtud6btm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Otud6btm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Otud6btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Otud6btm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Otud6btm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Otud6btm35854(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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