Otud6b | OTU domain containing 6B

GeneMGI:1919451Synonyms: 2600013N14Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hematopoietic system Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased basophil cell number	2 supporting datasets	Otud6b^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.71x10^-19
preweaning lethality, incomplete penetrance	1 supporting dataset	Otud6b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Otud6b.

Associated images

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Histopathology

There is no histopathology data found for Otud6b.

IMPC related publications

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External links

No external links available for Otud6b.

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*Otud6b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Otud6b^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Otud6b^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Otud6b^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Otud6b^{tm35854(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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