Megf6 | multiple EGF-like-domains 6

GeneMGI:1919351Synonyms: Egfl3, 2600001P17Rik

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Skeleton

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased total body fat amount1 supporting datasetMegf6em1(IMPC)KmpchomozygoteEarly adult7.67x10-6 
decreased bone mineral content1 supporting datasetMegf6em1(IMPC)KmpchomozygoteEarly adult4.81x10-5 
increased lean body mass1 supporting datasetMegf6em1(IMPC)KmpchomozygoteEarly adult5.11x10-7 
increased circulating cholesterol level1 supporting datasetMegf6em1(IMPC)KmpchomozygoteEarly adult5.3x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Megf6em1(IMPC)KmpcIndelmouse
Megf6tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell

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