Cotl1 | coactosin like F-actin binding protein 1
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Pigmentation Immune system Integument Vision/eye Hematopoietic system
14 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal coat/hair pigmentation | 3 supporting datasets | Cotl1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.48x10-12 | ||
| abnormal lens morphology | 4 supporting datasets | Cotl1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.5x10-7 | ||
| increased leukocyte cell number | 1 supporting dataset | Cotl1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.34x10-8 | ||
| decreased red blood cell distribution width | 1 supporting dataset | Cotl1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.93x10-5 |
| | | | | | | | | | |
External links
No external links available for Cotl1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Cotl1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Cotl1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Cotl1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |