Pdxp | pyridoxal (pyridoxine, vitamin B6) phosphatase
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Growth/size/body region Hematopoietic system Behavior/neurological Skeleton
12 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal bone structure | 1 supporting dataset | Pdxpem1(IMPC)J | homozygote | Early adult | 1.73x10-6 | ||
| increased leukocyte cell number | 1 supporting dataset | Pdxpem1(IMPC)J | homozygote | Early adult | 1.68x10-8 | ||
| decreased bone mineral content | 1 supporting dataset | Pdxpem1(IMPC)J | homozygote | Early adult | 2.86x10-5 | ||
| increased lean body mass | 2 supporting datasets | Pdxpem1(IMPC)J | homozygote | Early adult | 2.18x10-6 | ||
| hyperactivity | 1 supporting dataset | Pdxpem1(IMPC)J | homozygote | Early adult | 5.49x10-5 |
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Human diseases caused by Pdxp mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Pdxp.
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