C1qtnf1 | C1q and tumor necrosis factor related protein 1

GeneMGI:1919254Synonyms: 1600017K21Rik, CTRP1

Physiological systems

21 / 24 physiological systems tested

12 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Renal/urinary system

9 No significant impact

3 Not tested

Gene metrics:19Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal liver morphology1 supporting datasetC1qtnf1em1(IMPC)MbphomozygoteLate adultN/A * 
microphthalmia1 supporting datasetC1qtnf1em1(IMPC)MbphomozygoteLate adultN/A * 
small kidney1 supporting datasetC1qtnf1em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal kidney morphology1 supporting datasetC1qtnf1em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal ovary morphology1 supporting datasetC1qtnf1em1(IMPC)MbphomozygoteLate adultN/A * 
enlarged cecum1 supporting datasetC1qtnf1em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetC1qtnf1em1(IMPC)MbphomozygoteLate adultN/A * 
enlarged kidney2 supporting datasetsC1qtnf1em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal cecum morphology1 supporting datasetC1qtnf1em1(IMPC)MbphomozygoteLate adultN/A * 
enlarged spleen1 supporting datasetC1qtnf1em1(IMPC)MbphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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C1qtnf1em1(IMPC)MbpExon Deletionmouse
C1qtnf1tm41202(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
C1qtnf1tm41202(L1L2_st2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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