Ddx54 | DEAD box helicase 54

GeneMGI:1919240Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 54, DP97, +2 more

Physiological systems

22 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Mortality/aging Cardiovascular system

19 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:74Adult tissues

29Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Ddx54^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Ddx54^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Ddx54^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Ddx54^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ddx54.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ddx54.

IMPC related publications

Loading...

External links

No external links available for Ddx54.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ddx54^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Ddx54^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Ddx54^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ddx54^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes