Zswim1 | zinc finger SWIM-type containing 1
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Immune system Growth/size/body region Hematopoietic system
14 No significant impact
7 Not tested
Data collections
Gene metrics:16Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased neutrophil cell number | 2 supporting datasets | Zswim1tm1b(KOMP)Mbp | homozygote | Early adult | 1.19x10-26 | ||
| decreased hematocrit | 1 supporting dataset | Zswim1tm1b(KOMP)Mbp | homozygote | Early adult | 1.04x10-6 | ||
| increased erythrocyte cell number | 1 supporting dataset | Zswim1tm1b(KOMP)Mbp | homozygote | Early adult | 1.71x10-7 | ||
| decreased monocyte cell number | 1 supporting dataset | Zswim1tm1b(KOMP)Mbp | homozygote | Early adult | 1.92x10-8 | ||
| increased eosinophil cell number | 2 supporting datasets | Zswim1tm1b(KOMP)Mbp | homozygote | Early adult | 1.05x10-68 | ||
| increased lymphocyte cell number | 1 supporting dataset | Zswim1tm1b(KOMP)Mbp | homozygote | Early adult | 6.14x10-9 | ||
| decreased mean corpuscular volume | 1 supporting dataset | Zswim1tm1b(KOMP)Mbp | homozygote | Early adult | 2.76x10-18 | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Zswim1tm1b(KOMP)Mbp | homozygote | Early adult | 6.75x10-9 | ||
| increased leukocyte cell number | 1 supporting dataset | Zswim1tm1b(KOMP)Mbp | homozygote | Early adult | 3.96x10-10 | ||
| increased basophil cell number | 2 supporting datasets | Zswim1tm1b(KOMP)Mbp | homozygote | Early adult | 4.82x10-93 |
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Human diseases caused by Zswim1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Zswim1.
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| Zswim1tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Zswim1tm1b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Zswim1tm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |