Zswim1 | zinc finger SWIM-type containing 1

GeneMGI:1919221Synonyms: 2410003H12Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:16Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased neutrophil cell number2 supporting datasetsZswim1tm1b(KOMP)MbphomozygoteEarly adult1.19x10-26 
decreased hematocrit1 supporting datasetZswim1tm1b(KOMP)MbphomozygoteEarly adult1.04x10-6 
increased erythrocyte cell number1 supporting datasetZswim1tm1b(KOMP)MbphomozygoteEarly adult1.71x10-7 
decreased monocyte cell number1 supporting datasetZswim1tm1b(KOMP)MbphomozygoteEarly adult1.92x10-8 
increased eosinophil cell number2 supporting datasetsZswim1tm1b(KOMP)MbphomozygoteEarly adult1.05x10-68 
increased lymphocyte cell number1 supporting datasetZswim1tm1b(KOMP)MbphomozygoteEarly adult6.14x10-9 
decreased mean corpuscular volume1 supporting datasetZswim1tm1b(KOMP)MbphomozygoteEarly adult2.76x10-18 
decreased mean corpuscular hemoglobin1 supporting datasetZswim1tm1b(KOMP)MbphomozygoteEarly adult6.75x10-9 
increased leukocyte cell number1 supporting datasetZswim1tm1b(KOMP)MbphomozygoteEarly adult3.96x10-10 
increased basophil cell number2 supporting datasetsZswim1tm1b(KOMP)MbphomozygoteEarly adult4.82x10-93 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zswim1tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Zswim1tm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Zswim1tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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