Tmem94 | transmembrane protein 94
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Behavior/neurological Mortality/aging
13 No significant impact
7 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal tail movements | 1 supporting dataset | Tmem94tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 5.49x10-5 | ||
| decreased circulating sodium level | 1 supporting dataset | Tmem94tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.78x10-5 | ||
| increased mean corpuscular hemoglobin concentration | 1 supporting dataset | Tmem94tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 4.05x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Tmem94tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
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Human diseases caused by Tmem94 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Tmem94.
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| Tmem94tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Tmem94tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |